Engineering T cells with hypoxia-inducible chimeric antigen receptor (HiCAR) for selective tumor killing
Abstract Chimeric antigen receptor-modified T cells (CAR-T cells) have shown good effects in the treatment of hematologic cancers; however, they may cause on-target off-tumor toxicity because of minimal expression of tumor-associated antigens (TAAs) on normal tissues, particularly in the context of...
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Main Authors: | , , , , , |
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Format: | Book |
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BMC,
2020-10-01T00:00:00Z.
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Internet
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Call Number: |
A1234.567 |
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Copy 1 | Available |