Clinical Implications of 20-Hydroxyeicosatetraenoic Acid in the Kidney, Liver, Lung and Brain: An Emerging Therapeutic Target

• Главные авторы: Osama H. Elshenawy (Автор), Sherif M. Shoieb (Автор), Anwar Mohamed (Автор), Ayman O.S. El-Kadi (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2017-02-01T00:00:00Z.
• Предметы: article
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Cytochrome P450-mediated metabolism of arachidonic acid (AA) is an important pathway for the formation of eicosanoids. The ω-hydroxylation of AA generates significant levels of 20-hydroxyeicosatetraenoic acid (20-HETE) in various tissues. In the current review, we discussed the role of 20-HETE in th...