Clinical Implications of 20-Hydroxyeicosatetraenoic Acid in the Kidney, Liver, Lung and Brain: An Emerging Therapeutic Target

• मुख्य लेखकों: Osama H. Elshenawy (लेखक), Sherif M. Shoieb (लेखक), Anwar Mohamed (लेखक), Ayman O.S. El-Kadi (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2017-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Cytochrome P450-mediated metabolism of arachidonic acid (AA) is an important pathway for the formation of eicosanoids. The ω-hydroxylation of AA generates significant levels of 20-hydroxyeicosatetraenoic acid (20-HETE) in various tissues. In the current review, we discussed the role of 20-HETE in th...