Polymorphisms of SLCO1B1 Gene in Sundanese Ethnic Population of Tuberculosis Patients in Indonesia

• मुख्य लेखकों: Prayudi Santoso (लेखक), Henny Juliastuti (लेखक), Heda Melinda Nataprawira (लेखक), Arto Yuwono Soeroto (लेखक), Bachti Alisjahbana (लेखक), Rovina Ruslami (लेखक), Josephine Debora (लेखक), Yunia Sribudiani (लेखक), Ani Melani Maskoen (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Interna Publishing, 2022-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background: The blood level of rifampicin, one of the tuberculosis (TB) drugs, depends on the organic anion transporting polypeptide 1B1 (OATP1B1) in hepatocytes. This protein is encoded by the solute carrier organic anion 1B1 (SLCO1B1) gene. Its genetic variation has been reported to have an impact...