Polymorphisms of SLCO1B1 Gene in Sundanese Ethnic Population of Tuberculosis Patients in Indonesia

• Main Authors: Prayudi Santoso (Author), Henny Juliastuti (Author), Heda Melinda Nataprawira (Author), Arto Yuwono Soeroto (Author), Bachti Alisjahbana (Author), Rovina Ruslami (Author), Josephine Debora (Author), Yunia Sribudiani (Author), Ani Melani Maskoen (Author)
• Format: Book
• Published: Interna Publishing, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The blood level of rifampicin, one of the tuberculosis (TB) drugs, depends on the organic anion transporting polypeptide 1B1 (OATP1B1) in hepatocytes. This protein is encoded by the solute carrier organic anion 1B1 (SLCO1B1) gene. Its genetic variation has been reported to have an impact...