Scaling up for the industrial production of rifamycin B; optimization of the process conditions in bench-scale fermentor

• Asıl Yazarlar: Hewaida F. El-Sedawy (Yazar), Manal M.M. Hussein (Yazar), Tamer Essam (Yazar), Ossama M. El-Tayeb (Yazar), Fatma H.A. Mohammad (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Faculty of Pharmacy, Cairo University, 2013-06-01T00:00:00Z.
• Konular: article
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Optimization of fermentation process conditions using a gene amplified variant of Amycolatopsis mediterranei (NCH) was carried out. The use of aeration level 1.5 vvm increased the yield by 16.6% (from 13.81 to 16.1 g/l) upon controlling the temperature at 28 °C. Adjustment of the aeration level at 1...