Joint use of population pharmacokinetics and machine learning for optimizing antiepileptic treatment in pediatric population

• Asıl Yazarlar: Ivana Damnjanović (Yazar), Nastia Tsyplakova (Yazar), Nikola Stefanović (Yazar), Tatjana Tošić (Yazar), Aleksandra Catić-Đorđević (Yazar), Vangelis Karalis (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: SAGE Publishing, 2023-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Purpose: Unpredictable drug efficacy and safety of combined antiepileptic therapy is a major challenge during pharmacotherapy decisions in everyday clinical practice. The aim of this study was to describe the pharmacokinetics of valproic acid (VA), lamotrigine (LTG), and levetiracetam (LEV) in a ped...