Joint use of population pharmacokinetics and machine learning for optimizing antiepileptic treatment in pediatric population

• Hoofdauteurs: Ivana Damnjanović (Auteur), Nastia Tsyplakova (Auteur), Nikola Stefanović (Auteur), Tatjana Tošić (Auteur), Aleksandra Catić-Đorđević (Auteur), Vangelis Karalis (Auteur)
• Formaat: Boek
• Gepubliceerd in: SAGE Publishing, 2023-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Purpose: Unpredictable drug efficacy and safety of combined antiepileptic therapy is a major challenge during pharmacotherapy decisions in everyday clinical practice. The aim of this study was to describe the pharmacokinetics of valproic acid (VA), lamotrigine (LTG), and levetiracetam (LEV) in a ped...