Rational Strategy for Designing Peptidomimetic Small Molecules Based on Cyclic Peptides Targeting Protein-Protein Interaction between CTLA-4 and B7-1

• Main Authors: Kumiko Tsuihiji (Author), Eiji Honda (Author), Kanehisa Kojoh (Author), Shizue Katoh (Author), Tomonori Taguri (Author), Atsushi Yoshimori (Author), Hajime Takashima (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Currently, various pharmaceutical modalities are being developed rapidly. Targeting protein-protein interactions (PPIs) is an important objective in such development. Cyclic peptides, because they have good specificity and activity, have been attracting much attention as an alternative to antibody d...