Rational Strategy for Designing Peptidomimetic Small Molecules Based on Cyclic Peptides Targeting Protein-Protein Interaction between CTLA-4 and B7-1

• Hauptverfasser: Kumiko Tsuihiji (Verfasst von), Eiji Honda (Verfasst von), Kanehisa Kojoh (Verfasst von), Shizue Katoh (Verfasst von), Tomonori Taguri (Verfasst von), Atsushi Yoshimori (Verfasst von), Hajime Takashima (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2022-12-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Currently, various pharmaceutical modalities are being developed rapidly. Targeting protein-protein interactions (PPIs) is an important objective in such development. Cyclic peptides, because they have good specificity and activity, have been attracting much attention as an alternative to antibody d...