Rational Strategy for Designing Peptidomimetic Small Molecules Based on Cyclic Peptides Targeting Protein-Protein Interaction between CTLA-4 and B7-1

• Prif Awduron: Kumiko Tsuihiji (Awdur), Eiji Honda (Awdur), Kanehisa Kojoh (Awdur), Shizue Katoh (Awdur), Tomonori Taguri (Awdur), Atsushi Yoshimori (Awdur), Hajime Takashima (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2022-12-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Currently, various pharmaceutical modalities are being developed rapidly. Targeting protein-protein interactions (PPIs) is an important objective in such development. Cyclic peptides, because they have good specificity and activity, have been attracting much attention as an alternative to antibody d...