2-(4-Methylthiazol-5-yl) Ethyl Nitrate Hydrochloride Ameliorates Cognitive Impairment via Modulation of Oxidative Stress and Nuclear Factor Kappa B (NF-κB) Signaling Pathway in Chronic Cerebral Hypoperfusion-Associated Spontaneously Hypertensive Rats

Hypertension reduces the bioavailability of vascular nitric oxide (NO) and contributes to the onset of vascular dementia (VaD). A loss of NO bioavailability increases inflammation and oxidative stress. 2-(4-Methylthiazol-5-yl) ethyl nitrate hydrochloride (W1302) is a novel nitric oxide donor (NOD) w...

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Main Authors: Jiang Li (Author), Shaofeng Xu (Author), Ling Wang (Author), Xiaoliang Wang (Author)
Format: Book
Published: MDPI AG, 2024-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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