Functional candesartan loaded lipid nanoparticles for the control of diabetes-associated stroke: In vitro and in vivo studies

• Главные авторы: Dina M. Mahmoud (Автор), Mohammed R.A. Ali (Автор), Basmah Nasser Aldosari (Автор), Randa Mohammed Zaki (Автор), Obaid Afzal (Автор), Alaa S. Tulbah (Автор), Demiana M. Naguib (Автор), Mohamed I. Zanaty (Автор), Mary Eskander Attia (Автор), Fatma I. Abo El-Ela (Автор), Amr Gamal Fouad (Автор)
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• Опубликовано: Elsevier, 2024-06-01T00:00:00Z.
• Предметы: article
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Diabetes mellitus is a metabolic disease that raises the odds of developing stroke. Candesartan has been used to prevent stroke due to its inhibitory effects on blood pressure, angiogenesis, oxidative damage, and apoptosis. However, oral candesartan has very limited bioavailability and efficacy due...