Synthesis and cytotoxicity evaluation of thiosemicarbazones and their thiazole derivatives

• Auteurs principaux: Saulo Feheiberg Pinto Braga (Auteur), Nayara Cristina Fonseca (Auteur), Jonas Pereira Ramos (Auteur), Elaine Maria de Souza-Fagundes (Auteur), Renata Barbosa de Oliveira (Auteur)
• Format: Livre
• Publié: Universidade de São Paulo.
• Sujets: article
• Accès en ligne: Connect to this object online.

ABSTRACT The aims of this study were to synthesize a series of thiosemicarbazones and their thiazole derivatives, to investigate their cytotoxic activity against three human cancers and normal (Vero cells) cell lines, and to evaluate the pro-apoptotic potential of the most active compounds. Material...