Trimidox-Induced Apoptosis Is Mediated Through Induction of p53 in NALM-6 Cells

• Váldodahkkit: Syu-ichi Kanno (Dahkki), Takaharu Ohtake (Dahkki), Yuu Osanai (Dahkki), Kaori Kurauchi (Dahkki), Mayuko Ujibe (Dahkki), Koji Uwai (Dahkki), Mituhiro Takeshita (Dahkki), Susumu Satoh (Dahkki), Masaaki Ishikawa (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2008-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

We examined the effect of trimidox-induced apoptosis involvement of p53 in the NALM-6 cell line of acute lymphoblastic leukemia. Trimidox has been shown to increase the induction of p53. Phosphorylation of p53 protein at Ser-15 and Ser-20 residues was activated earlier than the obvious increase in p...