Simultaneous quantitation of atorvastatin and its two active metabolites in human plasma by liquid chromatography/(â) electrospray tandem mass spectrometry

• Autores principales: Pankaj Partani (Autor), S. Manaswita Verma (Autor), Sanjay Gurule (Autor), Arshad Khuroo (Autor), Tausif Monif (Autor)
• Formato: Libro
• Publicado: Elsevier, 2014-02-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

A sensitive, accurate and selective liquid chromatographyâtandem mass spectrometry method (LCâMS/MS) was developed and validated for the simultaneous quantitation of atorvastatin (AT) and its equipotent hydroxyl metabolites, 2-hydroxy atorvastatin (2-AT) and 4-hydroxy atorvastatin (4-AT), in human p...