Simultaneous quantitation of atorvastatin and its two active metabolites in human plasma by liquid chromatography/(â) electrospray tandem mass spectrometry

• Main Authors: Pankaj Partani (Author), S. Manaswita Verma (Author), Sanjay Gurule (Author), Arshad Khuroo (Author), Tausif Monif (Author)
• Format: Book
• Published: Elsevier, 2014-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A sensitive, accurate and selective liquid chromatographyâtandem mass spectrometry method (LCâMS/MS) was developed and validated for the simultaneous quantitation of atorvastatin (AT) and its equipotent hydroxyl metabolites, 2-hydroxy atorvastatin (2-AT) and 4-hydroxy atorvastatin (4-AT), in human p...