Simultaneous quantitation of atorvastatin and its two active metabolites in human plasma by liquid chromatography/(â) electrospray tandem mass spectrometry

• Egile Nagusiak: Pankaj Partani (Egilea), S. Manaswita Verma (Egilea), Sanjay Gurule (Egilea), Arshad Khuroo (Egilea), Tausif Monif (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2014-02-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

A sensitive, accurate and selective liquid chromatographyâtandem mass spectrometry method (LCâMS/MS) was developed and validated for the simultaneous quantitation of atorvastatin (AT) and its equipotent hydroxyl metabolites, 2-hydroxy atorvastatin (2-AT) and 4-hydroxy atorvastatin (4-AT), in human p...