Simultaneous quantitation of atorvastatin and its two active metabolites in human plasma by liquid chromatography/(â) electrospray tandem mass spectrometry

• 主要な著者: Pankaj Partani (著者), S. Manaswita Verma (著者), Sanjay Gurule (著者), Arshad Khuroo (著者), Tausif Monif (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2014-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

A sensitive, accurate and selective liquid chromatographyâtandem mass spectrometry method (LCâMS/MS) was developed and validated for the simultaneous quantitation of atorvastatin (AT) and its equipotent hydroxyl metabolites, 2-hydroxy atorvastatin (2-AT) and 4-hydroxy atorvastatin (4-AT), in human p...