Mechanisms of glabridin inhibition of integrin αIIbβ3 inside-out signals and NF-κB activation in human platelets

Abstract Background Platelets play a crucial role in cardiovascular diseases (CVDs) and are activated by endogenous agonists like collagen. These agonists initiate signal transduction through specific platelet receptors, resulting in platelet aggregation. Glabridin, a prenylated isoflavonoid found i...

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Main Authors: Wei-Chieh Huang (Author), Thanasekaran Jayakumar (Author), Joen-Rong Sheu (Author), Chih-Wei Hsia (Author), Chih-Hsuan Hsia (Author), Ting-Lin Yen (Author), Chao-Chien Chang (Author)
Format: Book
Published: BMC, 2023-06-01T00:00:00Z.
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