Mechanisms of glabridin inhibition of integrin αIIbβ3 inside-out signals and NF-κB activation in human platelets

• প্রধান লেখক: Wei-Chieh Huang (লেখক), Thanasekaran Jayakumar (লেখক), Joen-Rong Sheu (লেখক), Chih-Wei Hsia (লেখক), Chih-Hsuan Hsia (লেখক), Ting-Lin Yen (লেখক), Chao-Chien Chang (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: BMC, 2023-06-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract Background Platelets play a crucial role in cardiovascular diseases (CVDs) and are activated by endogenous agonists like collagen. These agonists initiate signal transduction through specific platelet receptors, resulting in platelet aggregation. Glabridin, a prenylated isoflavonoid found i...