Natural statin derivatives as potential therapy to reduce intestinal fluid loss in cholera.

• Váldodahkkit: Rattikarn Noitem (Dahkki), Pawin Pongkorpsakol (Dahkki), Chartchai Changsen (Dahkki), Yaowapa Sukpondma (Dahkki), Chittreeya Tansakul (Dahkki), Vatcharin Rukachaisirikul (Dahkki), Chatchai Muanprasat (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Public Library of Science (PLoS), 2022-12-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

As a leading cause of death in children under 5 years old, secretory diarrheas including cholera are characterized by excessive intestinal fluid secretion driven by enterotoxin-induced cAMP-dependent intestinal chloride transport. This study aimed to identify fungal bioactive metabolites possessing...