Natural statin derivatives as potential therapy to reduce intestinal fluid loss in cholera.

• Hauptverfasser: Rattikarn Noitem (Verfasst von), Pawin Pongkorpsakol (Verfasst von), Chartchai Changsen (Verfasst von), Yaowapa Sukpondma (Verfasst von), Chittreeya Tansakul (Verfasst von), Vatcharin Rukachaisirikul (Verfasst von), Chatchai Muanprasat (Verfasst von)
• Format: Buch
• Veröffentlicht: Public Library of Science (PLoS), 2022-12-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

As a leading cause of death in children under 5 years old, secretory diarrheas including cholera are characterized by excessive intestinal fluid secretion driven by enterotoxin-induced cAMP-dependent intestinal chloride transport. This study aimed to identify fungal bioactive metabolites possessing...