Multidose Streptozotocin Induction of Diabetes in BALB/c Mice Induces a Dominant Oxidative Macrophage and a Conversion of TH1 to TH2 Phenotypes During Disease Progression

• Hauptverfasser: Naxin Sun (Verfasst von), Guiwen Yang (Verfasst von), Heng Zhao (Verfasst von), Huub F. J. Savelkoul (Verfasst von), Liguo An (Verfasst von)
• Format: Buch
• Veröffentlicht: Hindawi Limited, 2005-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Macrophages (Mp) are implicated in both early and late phases in type 1 diabetes development. Recent study has suggested that a balance between reductive Mp (RMp) and oxidative Mp (OMp) is possible to regulate TH1/TH2 balance. The aim of this study is to investigate the redox status of peritoneal Mp...