Induced pluripotent stem cells inhibit bleomycin-induced pulmonary fibrosis in mice through suppressing TGF-β1/Smad-mediated epithelial to mesenchymal transition

• Main Authors: Yan Zhou (Author), Zhong He (Author), Yuan Gao (Author), Rui Zheng (Author), Xiaoye Zhang (Author), Li Zhao (Author), Mingqi Tan (Author)
• Format: Bog
• Udgivet: Frontiers Media S.A., 2016-11-01T00:00:00Z.
• Fag: article
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Pulmonary fibrosis is a progressive and irreversible fibrotic lung disorder with high mortality and few treatment options. Recently, induced pluripotent stem (iPS) cells have been considered as an ideal resource for stem cell-based therapy. Although an earlier study demonstrated the therapeutic effe...