Induced pluripotent stem cells inhibit bleomycin-induced pulmonary fibrosis in mice through suppressing TGF-β1/Smad-mediated epithelial to mesenchymal transition

• Päätekijät: Yan Zhou (Tekijä), Zhong He (Tekijä), Yuan Gao (Tekijä), Rui Zheng (Tekijä), Xiaoye Zhang (Tekijä), Li Zhao (Tekijä), Mingqi Tan (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2016-11-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Pulmonary fibrosis is a progressive and irreversible fibrotic lung disorder with high mortality and few treatment options. Recently, induced pluripotent stem (iPS) cells have been considered as an ideal resource for stem cell-based therapy. Although an earlier study demonstrated the therapeutic effe...