A Collision Coupling Model Governs the Activation of Neuronal GIRK1/2 Channels by Muscarinic-2 Receptors

The G protein-activated Inwardly Rectifying K+-channel (GIRK) modulates heart rate and neuronal excitability. Following G-Protein Coupled Receptor (GPCR)-mediated activation of heterotrimeric G proteins (Gαβγ), opening of the channel is obtained by direct binding of Gβγ subunits. Interestingly, GIRK...

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Main Authors: Shai Berlin (Author), Etay Artzy (Author), Reem Handklo-Jamal (Author), Uri Kahanovitch (Author), Hanna Parnas (Author), Nathan Dascal (Author), Daniel Yakubovich (Author)
Format: Book
Published: Frontiers Media S.A., 2020-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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