A Dual-Functioning 5ʹ-PPP-NS1shRNA that Activates a RIG-I Antiviral Pathway and Suppresses Influenza NS1
Retinoic acid-inducible gene-I (RIG-I) is a cytosolic pathogen sensor that is crucial against a number of viral infections. Many viruses have evolved to inhibit pathogen sensors to suppress host innate immune responses. In the case of influenza, nonstructural protein 1 (NS1) suppresses RIG-I functio...
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Main Authors: | , , , , , , , , , |
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Format: | Book |
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Elsevier,
2020-03-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |