Double Heterozygosity of BRCA2 and STK11 in Familial Breast Cancer Detected by Exome Sequencing

• Asıl Yazarlar: Mojgan ATAEI-KACHOUEI (Yazar), Javad NADAF (Yazar), Mohammad Taghi AKBARI (Yazar), Morteza ATRI (Yazar), Jacek MAJEWSKI (Yazar), Yasser RIAZALHOSSEINI (Yazar), Masoud GARSHASBI (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Tehran University of Medical Sciences, 2015-10-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Background: Germ-line mutations of BRCA1 and BRCA2 genes are responsible for approximately 25-30% of dominantly inherited familial breast cancers; still a big part of genetic component is unknown. The aim of this study was to investigate genetic causes of familial breast cancer in a pedigree with re...