Carbonic anhydrase 12 mutation modulates membrane stability and volume regulation of aquaporin 5

• मुख्य लेखकों: Soyoung Hwang (लेखक), Jung Yun Kang (लेखक), Min Jae Kim (लेखक), Dong Min Shin (लेखक), Jeong Hee Hong (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Patients carrying the carbonic anhydrase12 E143K mutation showed the dry mouth phenotype. The mechanism underlying the modulation of aquaporin 5 and function in the salivary glands by carbonic anhydrase12 remains unknown. In this study, we identified the mislocalised aquaporin 5 in the salivary glan...