Carbonic anhydrase 12 mutation modulates membrane stability and volume regulation of aquaporin 5

• Автори: Soyoung Hwang (Автор), Jung Yun Kang (Автор), Min Jae Kim (Автор), Dong Min Shin (Автор), Jeong Hee Hong (Автор)
• Формат: Книга
• Опубліковано: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Patients carrying the carbonic anhydrase12 E143K mutation showed the dry mouth phenotype. The mechanism underlying the modulation of aquaporin 5 and function in the salivary glands by carbonic anhydrase12 remains unknown. In this study, we identified the mislocalised aquaporin 5 in the salivary glan...