Design and In Vivo Pharmacokinetic Evaluation of Triamcinolone Acetonide Microcrystals-Loaded PLGA Microsphere for Increased Drug Retention in Knees after Intra-Articular Injection

• Asıl Yazarlar: Myoung Jin Ho (Yazar), Hoe Taek Jeong (Yazar), Sung Hyun Im (Yazar), Hyung Tae Kim (Yazar), Jeong Eun Lee (Yazar), Jun Soo Park (Yazar), Ha Ra Cho (Yazar), Dong Yoon Kim (Yazar), Young Wook Choi (Yazar), Joon Woo Lee (Yazar), Yong Seok Choi (Yazar), Myung Joo Kang (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2019-08-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

A novel polymeric microsphere (MS) containing micronized triamcinolone acetonide (TA) in a crystalline state was structured to provide extended drug retention in joints after intra-articular (IA) injection. Microcrystals with a median diameter of 1.7 μm were prepared by ultra-sonication met...