Propofol Induces Cardioprotection Against Ischemia-Reperfusion Injury via Suppression of Transient Receptor Potential Vanilloid 4 Channel

• Autores principales: Binbin Wang (Autor), Qiongfeng Wu (Autor), Jie Liao (Autor), Shaoshao Zhang (Autor), Huixia Liu (Autor), Cui Yang (Autor), Qian Dong (Autor), Ning Zhao (Autor), Zhengrong Huang (Autor), Kefang Guo (Autor), Yimei Du (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2019-10-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Ca2+ entry via the transient receptor potential vanilloid 4 (TRPV4) channel contributes to Ca2+ overload and triggers many pathophysiological conditions, including myocardial ischemia/reperfusion (I/R) injury. Propofol, a widely used intravenous anesthetic, attenuates myocardial I/R injury. However,...