Folic Acid Improves Parkin-Null <i>Drosophila</i> Phenotypes and Transiently Reduces Vulnerable Dopaminergic Neuron Mitochondrial Hydrogen Peroxide Levels and Glutathione Redox Equilibrium

Folic Acid Improves Parkin-Null <i>Drosophila</i> Phenotypes and Transiently Reduces Vulnerable Dopaminergic Neuron Mitochondrial Hydrogen Peroxide Levels and Glutathione Redox Equilibrium

Loss-of-function parkin mutations cause oxidative stress and degeneration of dopaminergic neurons in the substantia nigra. Several consequences of parkin mutations have been described; to what degree they contribute to selective neurodegeneration remains unclear. Specific factors initiating excessiv...

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Main Authors: Katherine L. Houlihan (Author), Petros P. Keoseyan (Author), Amber N. Juba (Author), Tigran Margaryan (Author), Max E. Voss (Author), Alexander M. Babaoghli (Author), Justin M. Norris (Author), Greg J. Adrian (Author), Artak Tovmasyan (Author), Lori M. Buhlman (Author)
Format: Book
Published: MDPI AG, 2022-10-01T00:00:00Z.
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3rd Floor Main Library

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