α7 Nicotinic Agonist AR-R17779 Protects Mice against 2,4,6-Trinitrobenzene Sulfonic Acid-Induced Colitis in a Spleen-Dependent Way

• 主要な著者: Andrea Grandi (著者), Irene Zini (著者), Lisa Flammini (著者), Anna M. Cantoni (著者), Valentina Vivo (著者), Vigilio Ballabeni (著者), Elisabetta Barocelli (著者), Simona Bertoni (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2017-11-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The existence of a cholinergic anti-inflammatory pathway negatively modulating the inflammatory and immune responses in various clinical conditions and experimental models has long been postulated. In particular, the protective involvement of the vagus nerve and of nicotinic Ach receptors (nAChRs) h...