Development, testing, parameterisation, and calibration of a human PBPK model for the plasticiser, di-(2-ethylhexyl) terephthalate (DEHTP) using in silico, in vitro and human biomonitoring data

A physiologically based pharmacokinetic model for di-(2-ethylhexyl) terephthalate (DEHTP) based on a refined model for di-(2-propylheptyl) phthalate (DPHP) was developed to interpret the metabolism and biokinetics of DEHTP following a single oral dose of 50 mg to three male volunteers. In vitro and...

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Bibliographic Details
Main Authors: Kevin McNally (Author), Craig Sams (Author), Alex Hogg (Author), George Loizou (Author)
Format: Book
Published: Frontiers Media S.A., 2023-02-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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