Characterization of N-acetyltransferase 1 and 2 polymorphisms and haplotype analysis for inflammatory bowel disease and sporadic colorectal carcinoma

• Hoofdauteurs: Cobbs Gary A (Auteur), Hein David W (Auteur), Doll Mark A (Auteur), Martini Benjamin D (Auteur), Crawford Nigel PS (Auteur), Colliver Daniel W (Auteur), Mahid Suhal S (Auteur), Petras Robert E (Auteur), Galandiuk Susan (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2007-05-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>N-acetyltransferase 1 (NAT1) and 2 (NAT2) are polymorphic isoenzymes responsible for the metabolism of numerous drugs and carcinogens. Acetylation catalyzed by NAT1 and NAT2 are important in metabolic activation of arylamines to elec...