IL-1 inhibition in systemic juvenile idiopathic arthritis

• Glavni autori: Gabriella Giancane (Autor), Francesca Minoia (Autor), Sergio Davì (Autor), Giulia Bracciolini (Autor), Alessandro Consolaro (Autor), Angelo Ravelli (Autor)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2016-12-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Systemic juvenile idiopathic arthritis (sJIA) is the form of childhood arthritis whose treatment is most challenging. The demonstration of the prominent involvement of interleukin (IL)-1 in disease pathogenesis has provided the rationale for the treatment with biologic medications that antagonize th...