IL-1 inhibition in systemic juvenile idiopathic arthritis

• Main Authors: Gabriella Giancane (Author), Francesca Minoia (Author), Sergio Davì (Author), Giulia Bracciolini (Author), Alessandro Consolaro (Author), Angelo Ravelli (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Systemic juvenile idiopathic arthritis (sJIA) is the form of childhood arthritis whose treatment is most challenging. The demonstration of the prominent involvement of interleukin (IL)-1 in disease pathogenesis has provided the rationale for the treatment with biologic medications that antagonize th...