Growth hormone releasing peptide-6 (GHRP-6) prevents doxorubicin-induced myocardial and extra-myocardial damages by activating prosurvival mechanisms

• Main Authors: Jorge Berlanga-Acosta (Author), Danay Cibrian (Author), Juan Valiente-Mustelier (Author), José Suárez-Alba (Author), Ariana García-Ojalvo (Author), Viviana Falcón-Cama (Author), Baohong Jiang (Author), Linlin Wang (Author), Gerardo Guillén-Nieto (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Dilated cardiomyopathy (DCM) is a fatal myocardial condition with ventricular structural changes and functional deficits, leading to systolic dysfunction and heart failure (HF). DCM is a frequent complication in oncologic patients receiving Doxorubicin (Dox). Dox is a highly cardiotoxi...