Growth hormone releasing peptide-6 (GHRP-6) prevents doxorubicin-induced myocardial and extra-myocardial damages by activating prosurvival mechanisms

• Autori principali: Jorge Berlanga-Acosta (Autore), Danay Cibrian (Autore), Juan Valiente-Mustelier (Autore), José Suárez-Alba (Autore), Ariana García-Ojalvo (Autore), Viviana Falcón-Cama (Autore), Baohong Jiang (Autore), Linlin Wang (Autore), Gerardo Guillén-Nieto (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Introduction: Dilated cardiomyopathy (DCM) is a fatal myocardial condition with ventricular structural changes and functional deficits, leading to systolic dysfunction and heart failure (HF). DCM is a frequent complication in oncologic patients receiving Doxorubicin (Dox). Dox is a highly cardiotoxi...