TLR2 Derangements Likely Play a Significant Role in the Inflammatory Response and Thrombosis in Patients with Ph(−) Classical Myeloproliferative Neoplasm

• Hoofdauteurs: Jen Chin Wang (Auteur), Guanfang Shi (Auteur), Chi Chen (Auteur), Ching Wong (Auteur), Vladimir Gotlieb (Auteur), Gardith Joseph (Auteur), Kiron V Nair (Auteur), Lakshmi Boyapati (Auteur), Enayati Ladan (Auteur), James T. Symanowski (Auteur), Lishi Sun (Auteur)
• Formaat: Boek
• Gepubliceerd in: Hindawi Limited, 2024-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

We investigated the role of toll-like receptors (TLRs) in inflammatory pathways in Philadelphia chromosome-negative myeloproliferative neoplasms (Ph(−)MPNs). TLR2 expression was increased in ET, PV, and MPN (grouped as (PV + (ET) + MF)), whereas TLR4 was elevated only in MPN. TLR3, 7, and 9 were not...