Resolution of acute inflammation induced by monosodium urate crystals (MSU) through neutrophil extracellular trap-MSU aggregate-mediated negative signaling

• Κύριοι συγγραφείς: Cheng-Hsun Lu (Συγγραφέας), Chieh-Yu Shen (Συγγραφέας), Ko-Jen Li (Συγγραφέας), Cheng-Han Wu (Συγγραφέας), Yu-Hsuan Chen (Συγγραφέας), Yu-Min Kuo (Συγγραφέας), Song-Chou Hsieh (Συγγραφέας), Chia-Li Yu (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: BMC, 2024-11-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Abstract Background Polymorphonuclear neutrophils (PMN) activation by monosodium urate crystals (MSU) is crucial to acute gouty arthritis and subsequent spontaneous remission within 7-10 days. Activated PMNs release neutrophil extracellular traps (NETs) that entrap MSU crystals, forming NET-MSU aggr...