The Chronotopic™ System for Pulsatile and Colonic Delivery of Active Molecules in the Era of Precision Medicine: Feasibility by 3D Printing via Fused Deposition Modeling (FDM)

• Hoofdauteurs: Alice Melocchi (Auteur), Marco Uboldi (Auteur), Francesco Briatico-Vangosa (Auteur), Saliha Moutaharrik (Auteur), Matteo Cerea (Auteur), Anastasia Foppoli (Auteur), Alessandra Maroni (Auteur), Luca Palugan (Auteur), Lucia Zema (Auteur), Andrea Gazzaniga (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2021-05-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The pulsatile-release Chronotopic™ system was conceived of as a drug-containing core surrounded by a coat made of swellable/soluble hydrophilic polymers, the latter being able to provide a programmable lag phase prior to drug liberation. This system was also proposed in a colon-targeting configurati...