The Chronotopic™ System for Pulsatile and Colonic Delivery of Active Molecules in the Era of Precision Medicine: Feasibility by 3D Printing via Fused Deposition Modeling (FDM)

• Glavni autori: Alice Melocchi (Autor), Marco Uboldi (Autor), Francesco Briatico-Vangosa (Autor), Saliha Moutaharrik (Autor), Matteo Cerea (Autor), Anastasia Foppoli (Autor), Alessandra Maroni (Autor), Luca Palugan (Autor), Lucia Zema (Autor), Andrea Gazzaniga (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2021-05-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

The pulsatile-release Chronotopic™ system was conceived of as a drug-containing core surrounded by a coat made of swellable/soluble hydrophilic polymers, the latter being able to provide a programmable lag phase prior to drug liberation. This system was also proposed in a colon-targeting configurati...