The Chronotopic™ System for Pulsatile and Colonic Delivery of Active Molecules in the Era of Precision Medicine: Feasibility by 3D Printing via Fused Deposition Modeling (FDM)

• 主要な著者: Alice Melocchi (著者), Marco Uboldi (著者), Francesco Briatico-Vangosa (著者), Saliha Moutaharrik (著者), Matteo Cerea (著者), Anastasia Foppoli (著者), Alessandra Maroni (著者), Luca Palugan (著者), Lucia Zema (著者), Andrea Gazzaniga (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2021-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The pulsatile-release Chronotopic™ system was conceived of as a drug-containing core surrounded by a coat made of swellable/soluble hydrophilic polymers, the latter being able to provide a programmable lag phase prior to drug liberation. This system was also proposed in a colon-targeting configurati...