Deletion of the App-Runx1 region in mice models human partial monosomy 21

• Главные авторы: Thomas Arbogast (Автор), Matthieu Raveau (Автор), Claire Chevalier (Автор), Valérie Nalesso (Автор), Doulaye Dembele (Автор), Hugues Jacobs (Автор), Olivia Wendling (Автор), Michel Roux (Автор), Arnaud Duchon (Автор), Yann Herault (Автор)
• Формат: ‌
• Опубликовано: The Company of Biologists, 2015-06-01T00:00:00Z.
• Предметы: article
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Partial monosomy 21 (PM21) is a rare chromosomal abnormality that is characterized by the loss of a variable segment along human chromosome 21 (Hsa21). The clinical phenotypes of this loss are heterogeneous and range from mild alterations to lethal consequences, depending on the affected region of H...