Shaping the "hot" immunogenic tumor microenvironment by nanoparticles co‐delivering oncolytic peptide and TGF‐β1 siRNA for boosting checkpoint blockade therapy

• मुख्य लेखकों: Cao Dai Phung (लेखक), Bao Loc Nguyen (लेखक), Jee‐Heon Jeong (लेखक), Jae‐Hoon Chang (लेखक), Sung Giu Jin (लेखक), Han‐Gon Choi (लेखक), Sae Kwang Ku (लेखक), Jong Oh Kim (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2023-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Induction of potent immune responses toward tumors remains challenging in cancer immunotherapy, in which it only showed benefits in a minority of patients with "hot" tumors, which possess pre‐existing effector immune cells within the tumor. In this study, we proposed a nanoparticl...