Shaping the "hot" immunogenic tumor microenvironment by nanoparticles co‐delivering oncolytic peptide and TGF‐β1 siRNA for boosting checkpoint blockade therapy

• Autores principales: Cao Dai Phung (Autor), Bao Loc Nguyen (Autor), Jee‐Heon Jeong (Autor), Jae‐Hoon Chang (Autor), Sung Giu Jin (Autor), Han‐Gon Choi (Autor), Sae Kwang Ku (Autor), Jong Oh Kim (Autor)
• Formato: Libro
• Publicado: Wiley, 2023-09-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract Induction of potent immune responses toward tumors remains challenging in cancer immunotherapy, in which it only showed benefits in a minority of patients with "hot" tumors, which possess pre‐existing effector immune cells within the tumor. In this study, we proposed a nanoparticl...