Synthesis and COX-2 Inhibitory Activity of 4-[(E)-2-(4-Oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethenyl]benzene-1-sulfonamide and Its Analogs

Some novel 3-phenyl-2-[(E)-2-phenylethenyl]-3,4-dihydroquinazolin-4-one derivatives possessing para-sulfonamides groups on the phenyl ring of the 2-phenylethenyl moiety have been synthesized and their COX-2 inhibitory activity evaluated. The stuctures of the synthesized compounds were confirmed&...

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Main Authors: Hayun (Author), Sumi Hudiyono (Author), Muhammad Hanafi (Author), Arry Yanuar (Author)
Formato: Livro
Publicado em: MDPI AG, 2012-11-01T00:00:00Z.
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