A systematic in vitro investigation on poly-arginine modified nanostructured lipid carrier: Pharmaceutical characteristics, cellular uptake, mechanisms and cytotoxicity

• मुख्य लेखकों: Mingshuang Sun (लेखक), Yunyun Gao (लेखक), Zhihong Zhu (लेखक), Huixin Wang (लेखक), Cuiyan Han (लेखक), Xinggang Yang (लेखक), Weisan Pan (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2017-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The aim of the present study was to develop a poly-arginine modified nanostructured lipid carrier (R-NLC) by fusion-emulsification method and to test its pharmaceutical characteristics. The influence of R-NLC on A549 cells like cellular uptake and cytotoxicity was also appraised using unmodified NLC...