A systematic in vitro investigation on poly-arginine modified nanostructured lipid carrier: Pharmaceutical characteristics, cellular uptake, mechanisms and cytotoxicity

• Váldodahkkit: Mingshuang Sun (Dahkki), Yunyun Gao (Dahkki), Zhihong Zhu (Dahkki), Huixin Wang (Dahkki), Cuiyan Han (Dahkki), Xinggang Yang (Dahkki), Weisan Pan (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2017-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The aim of the present study was to develop a poly-arginine modified nanostructured lipid carrier (R-NLC) by fusion-emulsification method and to test its pharmaceutical characteristics. The influence of R-NLC on A549 cells like cellular uptake and cytotoxicity was also appraised using unmodified NLC...