A systematic in vitro investigation on poly-arginine modified nanostructured lipid carrier: Pharmaceutical characteristics, cellular uptake, mechanisms and cytotoxicity

• Główni autorzy: Mingshuang Sun (Autor), Yunyun Gao (Autor), Zhihong Zhu (Autor), Huixin Wang (Autor), Cuiyan Han (Autor), Xinggang Yang (Autor), Weisan Pan (Autor)
• Format: Książka
• Wydane: Elsevier, 2017-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

The aim of the present study was to develop a poly-arginine modified nanostructured lipid carrier (R-NLC) by fusion-emulsification method and to test its pharmaceutical characteristics. The influence of R-NLC on A549 cells like cellular uptake and cytotoxicity was also appraised using unmodified NLC...