Platycodon grandiflorum Triggers Antitumor Immunity by Restricting PD-1 Expression of CD8+ T Cells in Local Tumor Microenvironment

• मुख्य लेखकों: Ruijie Yang (लेखक), Tianli Pei (लेखक), Ruifei Huang (लेखक), Yue Xiao (लेखक), Jiangna Yan (लेखक), Jinglin Zhu (लेखक), Chunli Zheng (लेखक), Wei Xiao (लेखक), Chao Huang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

In the tumor microenvironment (TME), the activation of programmed death-1 (PD-1)-programmed death ligand-1 (PD-L1) pathway is one of the main signals of immune escape and tumor deterioration. Clinically, the application of monoclonal antibodies slows down the progression of various malignancies and...