NQO1 Binds and Supports SIRT1 Function

• Asıl Yazarlar: Peter Tsvetkov (Yazar), Julia Adler (Yazar), Romano Strobelt (Yazar), Yaarit Adamovich (Yazar), Gad Asher (Yazar), Nina Reuven (Yazar), Yosef Shaul (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Silent information regulator 2-related enzyme 1 (SIRT1) is an NAD+-dependent class III deacetylase and a key component of the cellular metabolic sensing pathway. The requirement of NAD+ for SIRT1 activity led us to assume that NQO1, an NADH oxidoreductase producing NAD+, regulates SIRT1 activity. We...