NF-κB/HDAC1/SREBP1c pathway mediates the inflammation signal in progression of hepatic steatosis

• Główni autorzy: Yunwei Guo (Autor), Xiaoying Zhang (Autor), Zhiyun Zhao (Autor), Hongyun Lu (Autor), Bilun Ke (Autor), Xin Ye (Autor), Bin Wu (Autor), Jianping Ye (Autor)
• Format: Książka
• Wydane: Elsevier, 2020-05-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

The transcription factor nuclear factor kappa B (NF-κB) is activated in hepatocytes in the pathogenesis of hepatic steatosis. However, the action mechanism of NF-κB remains to be established in the hepatic steatosis. In this study, the P50 subunit of NF-κB was found to promote the hepatic steatosis...