NF-κB/HDAC1/SREBP1c pathway mediates the inflammation signal in progression of hepatic steatosis

• Main Authors: Yunwei Guo (Author), Xiaoying Zhang (Author), Zhiyun Zhao (Author), Hongyun Lu (Author), Bilun Ke (Author), Xin Ye (Author), Bin Wu (Author), Jianping Ye (Author)
• Format: Book
• Published: Elsevier, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The transcription factor nuclear factor kappa B (NF-κB) is activated in hepatocytes in the pathogenesis of hepatic steatosis. However, the action mechanism of NF-κB remains to be established in the hepatic steatosis. In this study, the P50 subunit of NF-κB was found to promote the hepatic steatosis...